The design for a hybrid Aquarium and Research-Development Center at Pier 28 on the San Francisco waterfront employs organic, metabolic, and self-generating materials. Artificial organisms – protocells that in time grow into artificial limestone – help to decrease levels of carbon dioxide while reinforcing the existing structure and building its own sea-wall reef, skeleton, and envelope. Researchers, students, and visitors share spaces for learning, interaction, and collaboration. The scheme offers protection for marine species and enhances biodiversity. The living architectural intervention is aimed as a long-term solution for coastal cities and other areas at risk from storms surges due to climate change.